YANG Tingting, PENG Jizhuo, LU Chengcheng, ZHANG Zicheng, WU Weixuan
Objective To systematically analyze the burden of disease of HIV/AIDS and prevalence in China from 1990 to 2019, and to provide evidence-based basis for optimizing HIV/AIDS prevention and control strategy in China. Methods The Global Burden of Disease 2019 (GBD 2019) database was used to select the mortality rate, disability-adjusted life years (DALYs), years of life lost (YLL) rate, years of healthy life lost due to disability (YLD) and other indicators of HIV/AIDS in Chinese population from 1990 to 2019. The Joinpoint regression model was used to analyze the trend of each indicator changing with years, gender and age. Origin software was used to make trend charts. Results From 1990 to 2019, the incidence of HIV/AIDS in the Chinese population increased from 0.82 per 100, 000 to 2.24 per 100, 000. The mortality rate increased from 0.23 per 100, 000 to 2.23 per 100, 000. The DALYs increased from 13.18 per 100, 000 to 98.15 per 100, 000. The YLL rate increased from 12.18 per 100, 000 to 92.10 per 100, 000. The YLD increased from 1.01 per 100, 000 to 6.05 per 100, 000. According to Joinpoint regression analysis, the standardized mortality rate, DALYs, YLL rate and YLD showed an overall upward trend, and AAPC was 7.1%, 6.4%, 6.6% and 5.5%, respectively, P<0.05. The burden of disease of HIV/AIDS in Chinese men of all ages was higher than that in women. Young and middle-aged people and elderly people were high-risk groups. Conclusions The burden of disease of AIDS in China has significantly increased over the past 30 years, and AIDS has a prominent impact on men, young adults and the elderly, highlighting the grim situation of AIDS prevention and control.